![]() The diagnosis of CBP is difficult and the treatment regimens are not always successful. This current review deals with the history, taxonomy and life cycle of phages, and their uses in veterinary and biomedicine, and the commercially available phage products.Ĭhronic bacterial prostatitis (CBP) is a long-lasting and crippling disease that strongly impacts the patient's quality of life. Bacteriophage or phage therapy is therefore very useful in various fields like medicine, veterinary science, dentistry, and even agriculture. These points favor the use of phages as alternative to antibiotics. Though bacteria develop resistance to phages rarely, they are less toxic with minimum adverse effects compared to antibiotics and occasionally needs repeated administration. To counteract antibiotic resistance, an increasing menace to the human community, phage therapy is a timely gift. ![]() Bacteriophages are used for the detection of bacteria, typing of bacteria, destruction of biofilms, phage ligand technology, bacteriophage therapy against various infections and phage display. Phages are unique antibacterial agents in their ability to increase their numbers only in the presence of bacterial targets. Twort and d’Herelle were the two scientists who identified bacteriophage, and contributed immensely to the field of phage therapy. Lytic cycle causes killing of the bacteria and this property is utilized for the phage therapy. Phages follow two patterns of life cycle as lytic and lysogenic cycle. Some phages like T4, T7 have an unique structure of having head and tail. There are 10 families of phages which include tailed and sessile phages. Bacteriophages belong to a group of viruses which have the greatest number of entities in it. Bacteriophages are the viruses which infect bacteria and hence, they are friends to human beings.
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